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Illumina-based RiboMethSeq approach for mapping of 2′-O-Me residues in RNA

RNA 2′-O-methylation is one of the ubiquitous nucleotide modifications found in many RNA types from Bacteria, Archaea and Eukarya. RNAs bearing 2′-O-methylations show increased resistance to degradation and enhanced stability in helices. While the exact role of each 2′-O-Me residue remained elusive,...

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Bibliografiske detaljer
Udgivet i:Nucleic Acids Res
Main Authors: Marchand, Virginie, Blanloeil-Oillo, Florence, Helm, Mark, Motorin, Yuri
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2016
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Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5027498/
https://ncbi.nlm.nih.gov/pubmed/27302133
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkw547
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