The peptidomimetic Vasotide targets two retinal VEGF receptors and reduces pathological angiogenesis in murine and nonhuman primate models of retinal disease

Blood vessel growth from preexisting vessels (angiogenesis) underlies many severe diseases including major blinding retinal diseases such as retinopathy of prematurity (ROP) and aged macular degeneration (AMD). This observation has driven development of antibody inhibitors that block a central facto...

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Bibliographic Details
Published in:Sci Transl Med
Main Authors: Sidman, Richard L., Li, Jianxue, Lawrence, Matthew, Hu, Wenzheng, Musso, Gary F., Giordano, Ricardo J., Cardó-Vila, Marina, Pasqualini, Renata, Arap, Wadih
Format: Artigo
Language:Inglês
Published: 2015
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4787616/
https://ncbi.nlm.nih.gov/pubmed/26468327
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scitranslmed.aac4882
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