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An Antimicrobial Peptidomimetic Induces Mucorales Cell Death through Mitochondria-Mediated Apoptosis

The incidence of mucormycosis has dramatically increased in immunocompromised patients. Moreover, the array of cellular targets whose inhibition results in fungal cell death is rather limited. Mitochondria have been mechanistically identified as central regulators of detoxification and virulence in...

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Detalhes bibliográficos
Main Authors: Barbu, E. Magda, Shirazi, Fazal, McGrath, Danielle M., Albert, Nathaniel, Sidman, Richard L., Pasqualini, Renata, Arap, Wadih, Kontoyiannis, Dimitrios P.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3789667/
https://ncbi.nlm.nih.gov/pubmed/24098573
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0076981
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