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Development and evaluation of solid dispersion of spironolactone using fusion method

INTRODUCTION: Solubility and dissolution of a poor water-soluble drug are the two major barriers for formulation scientists in development of drug delivery. Many of the potent drugs do not show the therapeutic effects due to solubility issues but may show toxicity issues when used in high doses. Sol...

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Bibliografski detalji
Izdano u:Int J Pharm Investig
Glavni autori: Shamsuddin, Fazil, Mohammad, Ansari, Shahid Husain, Ali, Javed
Format: Artigo
Jezik:Inglês
Izdano: Medknow Publications & Media Pvt Ltd 2016
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4787064/
https://ncbi.nlm.nih.gov/pubmed/27014621
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4103/2230-973X.176490
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