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Development and evaluation of solid dispersion of spironolactone using fusion method

INTRODUCTION: Solubility and dissolution of a poor water-soluble drug are the two major barriers for formulation scientists in development of drug delivery. Many of the potent drugs do not show the therapeutic effects due to solubility issues but may show toxicity issues when used in high doses. Sol...

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Detalhes bibliográficos
Publicado no:Int J Pharm Investig
Main Authors: Shamsuddin, Fazil, Mohammad, Ansari, Shahid Husain, Ali, Javed
Formato: Artigo
Idioma:Inglês
Publicado em: Medknow Publications & Media Pvt Ltd 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4787064/
https://ncbi.nlm.nih.gov/pubmed/27014621
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4103/2230-973X.176490
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