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FAM21 directs SNX27–retromer cargoes to the plasma membrane by preventing transport to the Golgi apparatus

The endosomal network maintains cellular homeostasis by sorting, recycling and degrading endocytosed cargoes. Retromer organizes the endosomal sorting pathway in conjunction with various sorting nexin (SNX) proteins. The SNX27–retromer complex has recently been identified as a major endosomal hub th...

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Bibliografiske detaljer
Udgivet i:Nat Commun
Main Authors: Lee, Seongju, Chang, Jaerak, Blackstone, Craig
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4786876/
https://ncbi.nlm.nih.gov/pubmed/26956659
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms10939
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