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Direct Interaction between the Voltage Sensors Produces Cooperative Sustained Deactivation in Voltage-gated H(+) Channel Dimers
The voltage-gated H(+) channel (Hv) is a voltage sensor domain-like protein consisting of four transmembrane segments (S1–S4). The native Hv structure is a homodimer, with the two channel subunits functioning cooperatively. Here we show that the two voltage sensor S4 helices within the dimer directl...
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| Publicado no: | J Biol Chem |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4786727/ https://ncbi.nlm.nih.gov/pubmed/26755722 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.666834 |
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