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The Cooperative Voltage Sensor Motion that Gates a Potassium Channel

The four arginine-rich S4 helices of a voltage-gated channel move outward through the membrane in response to depolarization, opening and closing gates to generate a transient ionic current. Coupling of voltage sensing to gating was originally thought to operate with the S4s moving independently fro...

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Detalhes bibliográficos
Main Authors: Pathak, Medha, Kurtz, Lisa, Tombola, Francesco, Isacoff, Ehud
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1414780/
https://ncbi.nlm.nih.gov/pubmed/15623895
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1085/jgp.200409197
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