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17 beta-estradiol mimics ligand activity of the c-erbB2 protooncogene product.

We report here the physical and functional interaction of estrogen with the ErbB2 protein p185c-erbB2. The ErbB2 protein immunoprecipitated from estrogen-treated [10(-8) to 10(-6) M 17 beta-estradiol (E2)] RC cells showed higher autophosphorylation activity than that from untreated cells. Likewise a...

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Detaylı Bibliyografya
Yayımlandı:Proc Natl Acad Sci U S A
Asıl Yazarlar: Matsuda, S, Kadowaki, Y, Ichino, M, Akiyama, T, Toyoshima, K, Yamamoto, T
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: National Academy of Sciences 1993
Konular:
Online Erişim:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC47866/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7902571/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.90.22.10803
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