17 beta-estradiol mimics ligand activity of the c-erbB2 protooncogene product.

We report here the physical and functional interaction of estrogen with the ErbB2 protein p185c-erbB2. The ErbB2 protein immunoprecipitated from estrogen-treated [10(-8) to 10(-6) M 17 beta-estradiol (E2)] RC cells showed higher autophosphorylation activity than that from untreated cells. Likewise a...

Full description

Bibliographic Details

Published in:	Proc Natl Acad Sci U S A
Main Authors:	Matsuda, S, Kadowaki, Y, Ichino, M, Akiyama, T, Toyoshima, K, Yamamoto, T
Format:	Artigo
Language:	Inglês
Published:	National Academy of Sciences 1993
Subjects:	Research Article
Online Access:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC47866/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7902571/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.90.22.10803
Tags:	Add Tag No Tags, Be the first to tag this record!