17 beta-estradiol mimics ligand activity of the c-erbB2 protooncogene product.

We report here the physical and functional interaction of estrogen with the ErbB2 protein p185c-erbB2. The ErbB2 protein immunoprecipitated from estrogen-treated [10(-8) to 10(-6) M 17 beta-estradiol (E2)] RC cells showed higher autophosphorylation activity than that from untreated cells. Likewise a...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Matsuda, S, Kadowaki, Y, Ichino, M, Akiyama, T, Toyoshima, K, Yamamoto, T
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 1993
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC47866/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7902571/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.90.22.10803
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