Δ(24)-Sterol Methyltransferase Plays an Important Role in the Growth and Development of Sporothrix schenckii and Sporothrix brasiliensis

Inhibition of Δ(24)-sterol methyltransferase (24-SMT) in Sporothrix schenckii sensu stricto and Sporothrix brasiliensis was investigated in vitro. The effects on fungal growth and sterol composition of the 24-SMT inhibitor 22-hydrazone-imidazolin-2-yl-chol-5-ene-3β-ol (H3) were compared to those of...

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Bibliographic Details
Published in:Front Microbiol
Main Authors: Borba-Santos, Luana P., Visbal, Gonzalo, Gagini, Thalita, Rodrigues, Anderson M., de Camargo, Zoilo P., Lopes-Bezerra, Leila M., Ishida, Kelly, de Souza, Wanderley, Rozental, Sonia
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2016
Subjects:
Microbiology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4786573/
https://ncbi.nlm.nih.gov/pubmed/27014234
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmicb.2016.00311
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