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Adamantylidene-substituted alkylphosphocholine TCAN26 is more active against Sporothrix schenckii than miltefosine

Sporotrichosis is the most frequent subcutaneous mycosis in the world and its increasing incidence has led to the search for new therapeutic options for its treatment. In this study, we demonstrated that three structural analogues of miltefosine (TCAN26, TC19, and TC70) showed inhibitory activity ag...

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Publicado en:Mem Inst Oswaldo Cruz
Main Authors: Borba-Santos, Luana Pereira, Ishida, Kelly, Calogeropoulou, Theodora, de Souza, Wanderley, Rozental, Sonia
Formato: Artigo
Idioma:Inglês
Publicado: Instituto Oswaldo Cruz, Ministério da Saúde 2016
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4981111/
https://ncbi.nlm.nih.gov/pubmed/27581121
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1590/0074-02760160088
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