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Adamantylidene-substituted alkylphosphocholine TCAN26 is more active against Sporothrix schenckii than miltefosine

Sporotrichosis is the most frequent subcutaneous mycosis in the world and its increasing incidence has led to the search for new therapeutic options for its treatment. In this study, we demonstrated that three structural analogues of miltefosine (TCAN26, TC19, and TC70) showed inhibitory activity ag...

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Détails bibliographiques
Publié dans:Mem Inst Oswaldo Cruz
Auteurs principaux: Borba-Santos, Luana Pereira, Ishida, Kelly, Calogeropoulou, Theodora, de Souza, Wanderley, Rozental, Sonia
Format: Artigo
Langue:Inglês
Publié: Instituto Oswaldo Cruz, Ministério da Saúde 2016
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4981111/
https://ncbi.nlm.nih.gov/pubmed/27581121
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1590/0074-02760160088
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