S-Adenosyl-l-Methionine Inhibitors Δ(24)-Sterol Methyltransferase and Δ(24(28))-Sterol Methylreductase as Possible Agents against Paracoccidioides brasiliensis

We studied the antiproliferative effects of three azasterol analogs [piperidyl-2-yl-5α-pregnan-3β,20(R)-diol (AZA-1), 22-piperidin-2-yl-pregnan-22(S),3β-diol (AZA-2), and 22-piperidin-3-yl-pregnan-22(S),3β-diol (AZA-3)] and their effects on the lipid composition of the pathogenic yeastlike phase of...

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Hlavní autoři: Visbal, Gonzalo, Alvarez, Alvaro, Moreno, Belisario, San-Blas, Gioconda
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2003
Témata:
Mechanisms of Action: Physiological Effects
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC182635/
https://ncbi.nlm.nih.gov/pubmed/12937003
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.47.9.2966-2970.2003
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