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S-Adenosyl-l-Methionine Inhibitors Δ(24)-Sterol Methyltransferase and Δ(24(28))-Sterol Methylreductase as Possible Agents against Paracoccidioides brasiliensis
We studied the antiproliferative effects of three azasterol analogs [piperidyl-2-yl-5α-pregnan-3β,20(R)-diol (AZA-1), 22-piperidin-2-yl-pregnan-22(S),3β-diol (AZA-2), and 22-piperidin-3-yl-pregnan-22(S),3β-diol (AZA-3)] and their effects on the lipid composition of the pathogenic yeastlike phase of...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Microbiology
2003
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC182635/ https://ncbi.nlm.nih.gov/pubmed/12937003 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.47.9.2966-2970.2003 |
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