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The Melanocortin Receptor Accessory Protein 2 promotes food intake through inhibition of the Prokineticin Receptor-1

The Melanocortin Receptor Accessory Protein 2 (MRAP2) is an important regulator of energy homeostasis and its loss causes severe obesity in rodents. MRAP2 mediates its action in part through the potentiation of the MC4R, however, it is clear that MRAP2 is expressed in tissues that do not express MC4...

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Publicat a:eLife
Autors principals: Chaly, Anna L, Srisai, Dollada, Gardner, Ellen E, Sebag, Julien A
Format: Artigo
Idioma:Inglês
Publicat: eLife Sciences Publications, Ltd 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4786424/
https://ncbi.nlm.nih.gov/pubmed/26829592
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.12397
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