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The Role of Epithelial Sodium Channel ENaC and the Apical Cl(-)/HCO(3)(-) Exchanger Pendrin in Compensatory Salt Reabsorption in the Setting of Na-Cl Cotransporter (NCC) Inactivation
BACKGROUND: The absence of NCC does not cause significant salt wasting in NCC deficient mice under basal conditions. We hypothesized that ENaC and pendrin play important roles in compensatory salt absorption in the setting of NCC inactivation, and their inhibition and/or downregulation can cause sig...
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| Publié dans: | PLoS One |
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| Auteurs principaux: | , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Public Library of Science
2016
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4786216/ https://ncbi.nlm.nih.gov/pubmed/26963391 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0150918 |
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