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Metabolic stressors disrupt proteome homeostasis to suppress malignancy
Within tumor cells the heat shock factor 1 (HSF1)-mediated stress response is constitutively mobilized to counter persistent proteotoxic stress, thus sustaining their fragile proteome homeostasis and supporting robust malignant phenotypes. Intriguingly, our new studies reveal that metabolic stressor...
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| Publicado no: | Mol Cell Oncol |
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| Autor principal: | |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Taylor & Francis
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4786015/ https://ncbi.nlm.nih.gov/pubmed/26973866 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/23723556.2014.1002718 |
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