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Leukocyte adhesion during hypoxia is mediated by HIF-1-dependent induction of β(2) integrin gene expression

Inflammatory responses are associated with significant changes in tissue metabolism. In particular, metabolic shifts during inflammation can result in significant tissue hypoxia, with resultant induction of hypoxia-responsive genes. Given this association, we hypothesized that leukocyte functional r...

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Bibliographische Detailangaben
Hauptverfasser: Kong, Tianqing, Eltzschig, Holger K., Karhausen, Jorn, Colgan, Sean P., Shelley, C. Simon
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2004
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC478589/
https://ncbi.nlm.nih.gov/pubmed/15235127
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0401339101
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