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Mucosal Protection by Hypoxia-Inducible Factor (HIF) Prolyl Hydroxylase Inhibition

A number of recent studies have implicated tissue hypoxia in both acute and chronic inflammatory diseases, particularly as they relate to mucosal surfaces involving epithelial cells. In this context, a protective role for the transcriptional regulator hypoxia-inducible factor (HIF) was demonstrated...

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Autors principals: Robinson, Andreas, Keely, Simon, Karhausen, Jörn, Gerich, Mark E., Furuta, Glenn T., P.Colgan, Sean
Format: Artigo
Idioma:Inglês
Publicat: 2008
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2194638/
https://ncbi.nlm.nih.gov/pubmed/18166352
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1053/j.gastro.2007.09.033
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