Contribution of epithelial innate immunity to systemic protection afforded by prolyl hydroxylase inhibition in murine colitis

Pharmacological stabilization of hypoxia-inducible factor (HIF) through prolyl hydroxylase (PHD) inhibition limits mucosal damage associated with models of murine colitis. However, little is known about how PHD inhibitors (PHDi) influence systemic immune function during mucosal inflammation or the r...

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Bibliografski detalji
Glavni autori: Keely, Simon, Campbell, Eric L., Baird, Alan W., Hansbro, Philip M., Shalwitz, Robert A., Kotsakis, Anna, McNamee, Eoin N., Eltzschig, Holger K., Kominsky, Douglas J., Colgan, Sean P.
Format: Artigo
Jezik:Inglês
Izdano: 2013
Teme:
Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3772994/
https://ncbi.nlm.nih.gov/pubmed/23695513
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mi.2013.29
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