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Alkenyl Carbonyl Derivatives in Enantioselective Redox Relay Heck Reactions: Accessing α,β-Unsaturated Systems

A highly enantio- and site selective Pd-catalyzed arylation of alkenes linked to carbonyl derivatives to yield α,β-unsaturated systems is reported. The high site selectivity is attributed to both a solvent effect and the polarized nature of the carbonyl group, both of which have been analyzed throug...

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Vydáno v:J Am Chem Soc
Hlavní autoři: Zhang, Chun, Santiago, Celine B., Kou, Lei, Sigman, Matthew S.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2015
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4785797/
https://ncbi.nlm.nih.gov/pubmed/26030059
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.5b04289
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