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Drug-drug interactions and QT prolongation as a commonly assessed cardiac effect - comprehensive overview of clinical trials
BACKGROUND: Proarrhythmia assessment is one of the major concerns for regulatory bodies and pharmaceutical industry. ICH guidelines recommending preclinical tests have been established in attempt to eliminate the risk of drug-induced arrhythmias. However, in the clinic, arrhythmia occurrence is dete...
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| Publié dans: | BMC Pharmacol Toxicol |
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| Auteurs principaux: | , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
BioMed Central
2016
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4785617/ https://ncbi.nlm.nih.gov/pubmed/26960809 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40360-016-0053-1 |
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