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A freestanding proofreading domain is required for protein synthesis quality control in Archaea

Threonyl-tRNA synthetase (ThrRS) participates in protein synthesis quality control by selectively editing the misacylated species Ser-tRNA(Thr). In bacteria and eukaryotes the editing function of ThrRS resides in a highly conserved N-terminal domain distant from the active site. Most archaeal ThrRS...

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Détails bibliographiques
Auteurs principaux: Korencic, Dragana, Ahel, Ivan, Schelert, James, Sacher, Meik, Ruan, Benfang, Stathopoulos, Constantinos, Blum, Paul, Ibba, Michael, Söll, Dieter
Format: Artigo
Langue:Inglês
Publié: National Academy of Sciences 2004
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC478561/
https://ncbi.nlm.nih.gov/pubmed/15240874
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0403926101
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