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A freestanding proofreading domain is required for protein synthesis quality control in Archaea
Threonyl-tRNA synthetase (ThrRS) participates in protein synthesis quality control by selectively editing the misacylated species Ser-tRNA(Thr). In bacteria and eukaryotes the editing function of ThrRS resides in a highly conserved N-terminal domain distant from the active site. Most archaeal ThrRS...
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| Главные авторы: | , , , , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
National Academy of Sciences
2004
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC478561/ https://ncbi.nlm.nih.gov/pubmed/15240874 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0403926101 |
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