1,2-Dithiole-3-Ones as Potent Inhibitors of the Bacterial 3-Ketoacyl Acyl Carrier Protein Synthase III (FabH)

The enzyme FabH catalyzes the initial step of fatty acid biosynthesis via a type II dissociated fatty acid synthase. The pivotal role of this essential enzyme, combined with its unique structural features and ubiquitous occurrence in bacteria, has made it an attractive new target for the development...

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書誌詳細

出版年:	Antimicrob Agents Chemother
主要な著者:	He, Xin, Reeve, Anne McElwee, Desai, Umesh R., Kellogg, Glen E., Reynolds, Kevin A.
フォーマット:	Artigo
言語:	Inglês
出版事項:	American Society for Microbiology (ASM) 2004
主題:	Chemistry; Biosynthesis
オンライン･アクセス:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC478545/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15273125/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/AAC.48.8.3093-3102.2004
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