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Impact of Cethromycin (ABT-773) Therapy on Microbiological, Histologic, Immunologic, and Respiratory Indices in a Murine Model of Mycoplasma pneumoniae Lower Respiratory Infection

Mycoplasma pneumoniae is a major etiologic agent of acute lower respiratory infections. We evaluated the antimicrobial and immunologic effects of cethromycin (ABT-773), a ketolide antibiotic, for the treatment of M. pneumoniae pneumonia in a mouse model. Eight-week-old BALB/c mice were inoculated in...

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Détails bibliographiques
Publié dans:Antimicrob Agents Chemother
Auteurs principaux: Ríos, Ana María, Mejías, Asunción, Chávez-Bueno, Susana, Fonseca-Aten, Mónica, Katz, Kathy, Hatfield, Jeanine, Gómez, Ana María, Jafri, Hasan S., McCracken, George H., Ramilo, Octavio, Hardy, Robert Doug
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology (ASM) 2004
Sujets:
Accès en ligne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC478543/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15273098/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/AAC.48.8.2897-2904.2004
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