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Pharmacodynamic Assessment of Clarithromycin in a Murine Model of Pneumococcal Pneumonia
The pharmacodynamic profile of clarithromycin (CLR) was evaluated with a murine model of pneumonia. Eight Streptococcus pneumoniae isolates, including three macrolide-sensitive and five macrolide-resistant strains, were inoculated intratracheally into immunocompromised ICR mice as 10(8)-CFU bacteria...
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| Hlavní autoři: | , , , , , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
American Society for Microbiology
2002
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC127127/ https://ncbi.nlm.nih.gov/pubmed/11959578 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.46.5.1425-1434.2002 |
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