Toward understanding and exploiting tumor heterogeneity

The extent of tumor heterogeneity is an emerging theme that researchers are only beginning to understand. How genetic and epigenetic heterogeneity affects tumor evolution and clinical progression is unknown. The precise nature of the environmental factors that influence this heterogeneity is also ye...

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Veröffentlicht in:Nat Med
Hauptverfasser: Alizadeh, Ash A, Aranda, Victoria, Bardelli, Alberto, Blanpain, Cedric, Bock, Christoph, Borowski, Christine, Caldas, Carlos, Califano, Andrea, Doherty, Michael, Elsner, Markus, Esteller, Manel, Fitzgerald, Rebecca, Korbel, Jan O, Lichter, Peter, Mason, Christopher E, Navin, Nicholas, Pe’er, Dana, Polyak, Kornelia, Roberts, Charles W M, Siu, Lillian, Snyder, Alexandra, Stower, Hannah, Swanton, Charles, Verhaak, Roel G W, Zenklusen, Jean C, Zuber, Johannes, Zucman-Rossi, Jessica
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2015
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4785013/
https://ncbi.nlm.nih.gov/pubmed/26248267
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nm.3915
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