Toward understanding and exploiting tumor heterogeneity

The extent of tumor heterogeneity is an emerging theme that researchers are only beginning to understand. How genetic and epigenetic heterogeneity affects tumor evolution and clinical progression is unknown. The precise nature of the environmental factors that influence this heterogeneity is also ye...

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Détails bibliographiques
Publié dans:Nat Med
Auteurs principaux: Alizadeh, Ash A, Aranda, Victoria, Bardelli, Alberto, Blanpain, Cedric, Bock, Christoph, Borowski, Christine, Caldas, Carlos, Califano, Andrea, Doherty, Michael, Elsner, Markus, Esteller, Manel, Fitzgerald, Rebecca, Korbel, Jan O, Lichter, Peter, Mason, Christopher E, Navin, Nicholas, Pe’er, Dana, Polyak, Kornelia, Roberts, Charles W M, Siu, Lillian, Snyder, Alexandra, Stower, Hannah, Swanton, Charles, Verhaak, Roel G W, Zenklusen, Jean C, Zuber, Johannes, Zucman-Rossi, Jessica
Format: Artigo
Langue:Inglês
Publié: 2015
Sujets:
Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4785013/
https://ncbi.nlm.nih.gov/pubmed/26248267
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nm.3915
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