Selection of a Relevant In Vitro Blood-Brain Barrier Model to Investigate Pro-Metastatic Features of Human Breast Cancer Cell Lines

Around 7–17% of metastatic breast cancer patients will develop brain metastases, associated with a poor prognosis. To reach the brain parenchyma, cancer cells need to cross the highly restrictive endothelium of the Blood-Brain Barrier (BBB). As treatments for brain metastases are mostly inefficient,...

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Veröffentlicht in:PLoS One
Hauptverfasser: Drolez, Aurore, Vandenhaute, Elodie, Julien, Sylvain, Gosselet, Fabien, Burchell, Joy, Cecchelli, Roméo, Delannoy, Philippe, Dehouck, Marie-Pierre, Mysiorek, Caroline
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2016
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4784983/
https://ncbi.nlm.nih.gov/pubmed/26958843
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0151155
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