ST6GALNAC5 Expression Decreases the Interactions between Breast Cancer Cells and the Human Blood-Brain Barrier

The ST6GALNAC5 gene that encodes an α2,6-sialyltransferase involved in the biosynthesis of α-series gangliosides, was previously identified as one of the genes that mediate breast cancer metastasis to the brain. We have shown that the expression of ST6GALNAC5 in MDA-MB-231 breast cancer cells result...

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Main Authors: Aurore Drolez, Elodie Vandenhaute, Clément Philippe Delannoy, Justine Hélène Dewald, Fabien Gosselet, Romeo Cecchelli, Sylvain Julien, Marie-Pierre Dehouck, Philippe Delannoy, Caroline Mysiorek
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI AG 2016-08-01
Colecção:International Journal of Molecular Sciences
Assuntos:
breast cancer
blood-brain barrier
gangliosides
GD1α
ST6GALNAC5
sialyltransferase
brain metastasis
Acesso em linha:http://www.mdpi.com/1422-0067/17/8/1309
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