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Miniaturization and Automation of a Human In Vitro Blood–Brain Barrier Model for the High-Throughput Screening of Compounds in the Early Stage of Drug Discovery

Central nervous system (CNS) diseases are one of the top causes of death worldwide. As there is a difficulty of drug penetration into the brain due to the blood–brain barrier (BBB), many CNS drugs treatments fail in clinical trials. Hence, there is a need to develop effective CNS drugs following str...

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發表在:Pharmaceutics
Main Authors: Moya, Elisa L. J., Vandenhaute, Elodie, Rizzi, Eleonora, Boucau, Marie-Christine, Hachani, Johan, Maubon, Nathalie, Gosselet, Fabien, Dehouck, Marie-Pierre
格式: Artigo
語言:Inglês
出版: MDPI 2021
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC8233835/
https://ncbi.nlm.nih.gov/pubmed/34208550
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/pharmaceutics13060892
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