Rapid Real-Time PCR Genotyping of Mutations Associated with Sulfadoxine-Pyrimethamine Resistance in Plasmodium falciparum

The resistance of Plasmodium falciparum to sulfadoxine-pyrimethamine (SP) is an emerging public health threat. Resistance to these drugs is associated with point mutations in the genes encoding dihydropteroate synthase (DHPS) and dihydrofolate reductase (DHFR). We describe here an assay using real-t...

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Bibliografiske detaljer
Main Authors: Alker, Alisa P., Mwapasa, Victor, Meshnick, Steven R.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2004
Fag:
Mechanisms of Resistance
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC478490/
https://ncbi.nlm.nih.gov/pubmed/15273102
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.48.8.2924-2929.2004
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