Rapid Real-Time PCR Genotyping of Mutations Associated with Sulfadoxine-Pyrimethamine Resistance in Plasmodium falciparum

The resistance of Plasmodium falciparum to sulfadoxine-pyrimethamine (SP) is an emerging public health threat. Resistance to these drugs is associated with point mutations in the genes encoding dihydropteroate synthase (DHPS) and dihydrofolate reductase (DHFR). We describe here an assay using real-t...

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Publicat a:Antimicrob Agents Chemother
Autors principals: Alker, Alisa P., Mwapasa, Victor, Meshnick, Steven R.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology (ASM) 2004
Matèries:
Mechanisms of Resistance
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC478490/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15273102/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/AAC.48.8.2924-2929.2004
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