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Rapid Real-Time PCR Genotyping of Mutations Associated with Sulfadoxine-Pyrimethamine Resistance in Plasmodium falciparum

The resistance of Plasmodium falciparum to sulfadoxine-pyrimethamine (SP) is an emerging public health threat. Resistance to these drugs is associated with point mutations in the genes encoding dihydropteroate synthase (DHPS) and dihydrofolate reductase (DHFR). We describe here an assay using real-t...

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Detalhes bibliográficos
Main Authors: Alker, Alisa P., Mwapasa, Victor, Meshnick, Steven R.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC478490/
https://ncbi.nlm.nih.gov/pubmed/15273102
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.48.8.2924-2929.2004
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