Plasmodium falciparum Isolates in India Exhibit a Progressive Increase in Mutations Associated with Sulfadoxine-Pyrimethamine Resistance

The combination of sulfadoxine-pyrimethamine (SP) is used as a second line of therapy for the treatment of uncomplicated chloroquine-resistant Plasmodium falciparum malaria. Resistance to SP arises due to certain point mutations in the genes for the dihydrofolate reductase (DHFR) and dihydropteroate...

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Autori principali: Ahmed, Anwar, Bararia, Deepak, Vinayak, Sumiti, Yameen, Mohammed, Biswas, Sukla, Dev, Vas, Kumar, Ashwani, Ansari, Musharraf A., Sharma, Yagya D.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2004
Soggetti:
Mechanisms of Resistance
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC353157/
https://ncbi.nlm.nih.gov/pubmed/14982779
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.48.3.879-889.2004
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