Plasmodium falciparum Isolates in India Exhibit a Progressive Increase in Mutations Associated with Sulfadoxine-Pyrimethamine Resistance

The combination of sulfadoxine-pyrimethamine (SP) is used as a second line of therapy for the treatment of uncomplicated chloroquine-resistant Plasmodium falciparum malaria. Resistance to SP arises due to certain point mutations in the genes for the dihydrofolate reductase (DHFR) and dihydropteroate...

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Détails bibliographiques
Publié dans:Antimicrob Agents Chemother
Auteurs principaux: Ahmed, Anwar, Bararia, Deepak, Vinayak, Sumiti, Yameen, Mohammed, Biswas, Sukla, Dev, Vas, Kumar, Ashwani, Ansari, Musharraf A., Sharma, Yagya D.
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology (ASM) 2004
Sujets:
Mechanisms of Resistance
Accès en ligne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC353157/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14982779/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/AAC.48.3.879-889.2004
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