Susceptibility to Thrombin-Induced Platelet Microbicidal Protein Is Associated with Increased Fluconazole Efficacy against Experimental Endocarditis Due to Candida albicans

Platelet microbicidal proteins (PMPs) are believed to be integral to host defense against endovascular infection. We previously demonstrated that susceptibility to thrombin-induced PMP 1 (tPMP-1) in vitro negatively influences Candida albicans virulence in the rabbit model of infective endocarditis...

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Autors principals: Yeaman, Michael R., Cheng, Darwin, Desai, Bhavesh, Kupferwasser, Leon I., Xiong, Yan-Qiong, Gank, Kimberly D., Edwards, John E., Bayer, Arnold S.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2004
Matèries:
Experimental Therapeutics
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC478484/
https://ncbi.nlm.nih.gov/pubmed/15273120
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.48.8.3051-3056.2004
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