Susceptibility to Thrombin-Induced Platelet Microbicidal Protein Is Associated with Increased Fluconazole Efficacy against Experimental Endocarditis Due to Candida albicans

Platelet microbicidal proteins (PMPs) are believed to be integral to host defense against endovascular infection. We previously demonstrated that susceptibility to thrombin-induced PMP 1 (tPMP-1) in vitro negatively influences Candida albicans virulence in the rabbit model of infective endocarditis...

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Detalhes bibliográficos
Main Authors: Yeaman, Michael R., Cheng, Darwin, Desai, Bhavesh, Kupferwasser, Leon I., Xiong, Yan-Qiong, Gank, Kimberly D., Edwards, John E., Bayer, Arnold S.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2004
Assuntos:
Experimental Therapeutics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC478484/
https://ncbi.nlm.nih.gov/pubmed/15273120
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.48.8.3051-3056.2004
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