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Susceptibility to Thrombin-Induced Platelet Microbicidal Protein Is Associated with Increased Fluconazole Efficacy against Experimental Endocarditis Due to Candida albicans

Platelet microbicidal proteins (PMPs) are believed to be integral to host defense against endovascular infection. We previously demonstrated that susceptibility to thrombin-induced PMP 1 (tPMP-1) in vitro negatively influences Candida albicans virulence in the rabbit model of infective endocarditis...

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發表在:Antimicrob Agents Chemother
Main Authors: Yeaman, Michael R., Cheng, Darwin, Desai, Bhavesh, Kupferwasser, Leon I., Xiong, Yan-Qiong, Gank, Kimberly D., Edwards, John E., Bayer, Arnold S.
格式: Artigo
語言:Inglês
出版: American Society for Microbiology (ASM) 2004
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在線閱讀:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC478484/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15273120/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/AAC.48.8.3051-3056.2004
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