Susceptibility to Thrombin-Induced Platelet Microbicidal Protein Is Associated with Increased Fluconazole Efficacy against Experimental Endocarditis Due to Candida albicans

Platelet microbicidal proteins (PMPs) are believed to be integral to host defense against endovascular infection. We previously demonstrated that susceptibility to thrombin-induced PMP 1 (tPMP-1) in vitro negatively influences Candida albicans virulence in the rabbit model of infective endocarditis...

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Main Authors: Yeaman, Michael R., Cheng, Darwin, Desai, Bhavesh, Kupferwasser, Leon I., Xiong, Yan-Qiong, Gank, Kimberly D., Edwards, John E., Bayer, Arnold S.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2004
Assuntos:
Experimental Therapeutics
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC478484/
https://ncbi.nlm.nih.gov/pubmed/15273120
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.48.8.3051-3056.2004
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