Susceptibility to Thrombin-Induced Platelet Microbicidal Protein Is Associated with Increased Fluconazole Efficacy against Experimental Endocarditis Due to Candida albicans

Platelet microbicidal proteins (PMPs) are believed to be integral to host defense against endovascular infection. We previously demonstrated that susceptibility to thrombin-induced PMP 1 (tPMP-1) in vitro negatively influences Candida albicans virulence in the rabbit model of infective endocarditis...

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Autori principali: Yeaman, Michael R., Cheng, Darwin, Desai, Bhavesh, Kupferwasser, Leon I., Xiong, Yan-Qiong, Gank, Kimberly D., Edwards, John E., Bayer, Arnold S.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2004
Soggetti:
Experimental Therapeutics
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC478484/
https://ncbi.nlm.nih.gov/pubmed/15273120
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.48.8.3051-3056.2004
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