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DepR1, a TetR Family Transcriptional Regulator, Positively Regulates Daptomycin Production in an Industrial Producer, Streptomyces roseosporus SW0702

Daptomycin is a potent cyclic lipopeptide antibiotic. It is widely used against various Gram-positive bacterial pathogens. Historically, a poor understanding of the transcriptional regulation of daptomycin biosynthesis has limited the options for targeted genetic engineering toward titer improvement...

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Detalhes bibliográficos
Publicado no:Appl Environ Microbiol
Main Authors: Yuan, Peng-Hui, Zhou, Ri-Cheng, Chen, Xuepeng, Luo, Shuai, Wang, Feng, Mao, Xu-Ming, Li, Yong-Quan
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4784024/
https://ncbi.nlm.nih.gov/pubmed/26773081
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AEM.03002-15
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