A MarR Family Transcriptional Regulator, DptR3, Activates Daptomycin Biosynthesis and Morphological Differentiation in Streptomyces roseosporus

Daptomycin produced by Streptomyces roseosporus is an important lipopeptide antibiotic used to treat human infections caused by Gram-positive pathogenic bacteria, including drug-resistant strains. The genetic basis for regulatory mechanisms of daptomycin production is poorly known. Here, we characte...

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Detalhes bibliográficos
Publicado no:Appl Environ Microbiol
Main Authors: Zhang, Qinling, Chen, Qiong, Zhuang, Shuai, Chen, Zhi, Wen, Ying, Li, Jilun
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2015
Assuntos:
Genetics and Molecular Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4421045/
https://ncbi.nlm.nih.gov/pubmed/25819953
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AEM.00057-15
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