A MarR Family Transcriptional Regulator, DptR3, Activates Daptomycin Biosynthesis and Morphological Differentiation in Streptomyces roseosporus

Daptomycin produced by Streptomyces roseosporus is an important lipopeptide antibiotic used to treat human infections caused by Gram-positive pathogenic bacteria, including drug-resistant strains. The genetic basis for regulatory mechanisms of daptomycin production is poorly known. Here, we characte...

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Dades bibliogràfiques
Publicat a:Appl Environ Microbiol
Autors principals: Zhang, Qinling, Chen, Qiong, Zhuang, Shuai, Chen, Zhi, Wen, Ying, Li, Jilun
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2015
Matèries:
Genetics and Molecular Biology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4421045/
https://ncbi.nlm.nih.gov/pubmed/25819953
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AEM.00057-15
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