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Characterization of age‐associated exhausted CD8(+) T cells defined by increased expression of Tim‐3 and PD‐1

Aging is accompanied by altered T‐cell responses that result in susceptibility to various diseases. Previous findings on the increased expression of inhibitory receptors, such as programmed cell death protein 1 (PD‐1), in the T cells of aged mice emphasize the importance of investigations into the r...

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Detalhes bibliográficos
Publicado no:Aging Cell
Main Authors: Lee, Kyoo‐A, Shin, Kwang‐Soo, Kim, Ga‐Young, Song, You Chan, Bae, Eun‐Ah, Kim, Il‐Kyu, Koh, Choong‐Hyun, Kang, Chang‐Yuil
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4783346/
https://ncbi.nlm.nih.gov/pubmed/26750587
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.12435
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