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IL-21-mediated reversal of NK cell exhaustion facilitates anti-tumour immunity in MHC class I-deficient tumours
During cancer immunoediting, loss of major histocompatibility complex class I (MHC-I) in neoplasm contributes to the evasion of tumours from host immune system. Recent studies have demonstrated that most natural killer (NK) cells that are found in advanced cancers are defective, releasing the malign...
Wedi'i Gadw mewn:
| Cyhoeddwyd yn: | Nat Commun |
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| Prif Awduron: | , , , , , , , , , , , , , , , , , |
| Fformat: | Artigo |
| Iaith: | Inglês |
| Cyhoeddwyd: |
Nature Publishing Group
2017
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| Pynciau: | |
| Mynediad Ar-lein: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5467212/ https://ncbi.nlm.nih.gov/pubmed/28585539 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms15776 |
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