Activation of TRAIL‐DR5 pathway promotes sensorineural degeneration in the inner ear

Tumor necrosis factor (TNF) family cytokines are important mediators of inflammation. Elevated levels of serum TNF‐α are associated with human sensorineural hearing loss via poorly understood mechanisms. We demonstrate, for the first time, expression of TNF‐related apoptosis‐inducing ligand (TRAIL)...

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Udgivet i:Aging Cell
Main Authors: Kao, Shyan‐Yuan, Soares, Vitor Y.R., Kristiansen, Arthur G., Stankovic, Konstantina M.
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley and Sons Inc. 2016
Fag:
Original Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4783338/
https://ncbi.nlm.nih.gov/pubmed/26791792
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.12437
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