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Activation of TRAIL‐DR5 pathway promotes sensorineural degeneration in the inner ear

Tumor necrosis factor (TNF) family cytokines are important mediators of inflammation. Elevated levels of serum TNF‐α are associated with human sensorineural hearing loss via poorly understood mechanisms. We demonstrate, for the first time, expression of TNF‐related apoptosis‐inducing ligand (TRAIL)...

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Detalles Bibliográficos
Publicado en:Aging Cell
Main Authors: Kao, Shyan‐Yuan, Soares, Vitor Y.R., Kristiansen, Arthur G., Stankovic, Konstantina M.
Formato: Artigo
Idioma:Inglês
Publicado: John Wiley and Sons Inc. 2016
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4783338/
https://ncbi.nlm.nih.gov/pubmed/26791792
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.12437
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