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Activation of TRAIL‐DR5 pathway promotes sensorineural degeneration in the inner ear

Tumor necrosis factor (TNF) family cytokines are important mediators of inflammation. Elevated levels of serum TNF‐α are associated with human sensorineural hearing loss via poorly understood mechanisms. We demonstrate, for the first time, expression of TNF‐related apoptosis‐inducing ligand (TRAIL)...

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Detalhes bibliográficos
Publicado no:Aging Cell
Main Authors: Kao, Shyan‐Yuan, Soares, Vitor Y.R., Kristiansen, Arthur G., Stankovic, Konstantina M.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4783338/
https://ncbi.nlm.nih.gov/pubmed/26791792
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.12437
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