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Activation of TRAIL‐DR5 pathway promotes sensorineural degeneration in the inner ear

Tumor necrosis factor (TNF) family cytokines are important mediators of inflammation. Elevated levels of serum TNF‐α are associated with human sensorineural hearing loss via poorly understood mechanisms. We demonstrate, for the first time, expression of TNF‐related apoptosis‐inducing ligand (TRAIL)...

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Bibliographische Detailangaben
Veröffentlicht in:Aging Cell
Hauptverfasser: Kao, Shyan‐Yuan, Soares, Vitor Y.R., Kristiansen, Arthur G., Stankovic, Konstantina M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: John Wiley and Sons Inc. 2016
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4783338/
https://ncbi.nlm.nih.gov/pubmed/26791792
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.12437
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