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Loss of osteoprotegerin expression in the inner ear causes degeneration of the cochlear nerve and sensorineural hearing loss

Osteoprotegerin (OPG) is a key regulator of bone remodeling. Mutations and variations in the OPG gene cause many human diseases that are characterized by not only skeletal abnormalities but also poorly understood hearing loss: Paget’s disease, osteoporosis, and celiac disease. To gain insight into m...

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Detalhes bibliográficos
Main Authors: Kao, Shyan-Yuan, Kempfle, Judith S., Jensen, Jane B., Perez-Fernandez, Deborah, Lysaght, Andrew C., Edge, Albert S., Stankovic, Konstantina M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3752395/
https://ncbi.nlm.nih.gov/pubmed/23607938
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nbd.2013.04.008
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