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Noncompetitive affinity assays of glucagon and amylin using mirror-image aptamers as affinity probes
The ability to detect picomolar concentrations of glucagon and amylin using fluorescently labeled mirror-image aptamers, so-called Spiegelmers, is demonstrated. Spiegelmers rival the specificity of antibodies and overcome the problem of biostability of natural aptamers in a biological matrix. Using...
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| Publicado no: | Analyst |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4783278/ https://ncbi.nlm.nih.gov/pubmed/26881276 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c5an02468d |
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