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Continuous Signal Enhancement for Sensitive Aptamer Affinity Probe Electrophoresis Assay Using Electrokinetic Concentration

We describe an electrokinetic concentration-enhanced aptamer affinity probe electrophoresis assay to achieve highly sensitive and quantitative detection of protein targets in a microfluidic device. The key weaknesses of aptamer as a binding agent (weak binding strength/fast target dissociation) were...

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Bibliografski detalji
Glavni autori: Cheow, Lih Feng, Han, Jongyoon
Format: Artigo
Jezik:Inglês
Izdano: 2011
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3179849/
https://ncbi.nlm.nih.gov/pubmed/21809885
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ac201307d
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