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Probing the Limits of Aptamer Affinity with a Microfluidic SELEX Platform
Nucleic acid-based aptamers offer many potential advantages relative to antibodies and other protein-based affinity reagents, including facile chemical synthesis, reversible folding, improved thermal stability and lower cost. However, their selection requires significant time and resources and selec...
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| 主要な著者: | , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Public Library of Science
2011
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3215713/ https://ncbi.nlm.nih.gov/pubmed/22110600 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0027051 |
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