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The effect of local sequence context on mutational bias of leading and lagging strand genes

All organisms must replicate their genetic information accurately to ensure its faithful transmission. DNA polymerase errors provide an important source of genetic variation that can drive evolution. Understanding the origins of genetic variation will inform our understanding of evolution and the de...

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Detalhes bibliográficos
Publicado no:Curr Biol
Main Authors: Schroeder, Jeremy W., Hirst, William G., Szewczyk, Gabriella A., Simmons, Lyle A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4783269/
https://ncbi.nlm.nih.gov/pubmed/26923786
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cub.2016.01.016
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